You may not make .NET 5 WPF application executed in Android and IOS.
.Net core 5 can be installed on Windows, macOS, and Linux, for x86, x64, Arm32, Arm64.
The most significant addition for .NET 5.0 is Windows Arm64. So compared to net3.1, it's just more Arm64. For more details about .Net core 5, you can refer to Announcing .NET 5.0
If you want to create apps that can run in IOS and Android with C# code, you can use Xamarin which let you build native apps for Android, iOS, and macOS using .NET code and platform-specific user interfaces. Looking forward, the .NET 6.0 may come out in November 2021, Xamarin developers can use the unified .NET platform when we release .NET 6.0.
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