@AzureJP Microsoft Defender Antivirus needs monthly updates which also know as platform updates.
You will have to use any of the distributions method of updates that you use already (Any one) :
1) Windows Server Update Service (WSUS)
2) Microsoft Endpoint Configuration Manager
3) The usual method you use to deploy Microsoft and Windows updates to endpoints in your network.
You can choose Microsoft endpoint manager (Intune) to push these updates :
You can choose Group policy
Read more options here and here
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