It should stay disabled.
Note you could just replace the cert, assign SMTP to it and manually update the connectors. Its not required to run the Wizard.
[PS] C:\>$cert = Get-ExchangeCertificate -Thumbprint DE67EC3C8D679AA35D17678FEC51907272B1BAE2
[PS] C:\>$tlscertificatename = "<i>$($cert.Issuer)<s>$($cert.Subject)"
[PS] C:\>Set-ReceiveConnector "EX2016SRV1\HybridRecConnector" -TlsCertificateName $tlscertificatename
Then do the same for the send connector
Set-SendConnector -Identity “Send Connector Name” -TLSCertificateName $tlscertificatename