Hi, @Boopathi Subramaniam
Thank you for posting in Microsoft Q&A forum.
We can specify a String array for ApplicationName like below:
$dps = Get-Content "C:\Users\xy9764\Desktop\sp.txt"
foreach ($dp in $dps)
{
Remove-CMContentDistribution -ApplicationName ("Application name 1","Application name 2","Application name 3") -DistributionPointName "$dp"
}
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