question

Hello,

I don't think shift-deleting log files in inetpub would have caused this. Did you end up freeing space? Sometimes these errors can be related to insufficient space. How often is a full system backup (w/ System State) taken on the server? A full backup on Exchange will free up log space.

Once space has been cleared, are you able to reset exchange services (after hours or when use is minimal)?

Powershell script:

 $services = Get-Service | ? { $_.name -like "MSExchange*" -and $_.Status -eq "Running"}
     
 #Restart each service
 foreach ($service in $services)
 {
     Restart-Service $service.name -Force
 }

@Bundoo-2912

What's the detailed version of your Exchange 2013? You can check with the following command:

 Get-ExchangeServer | Format-List Name,Edition,AdminDisplayVersion

What error message do you get after entering the URL of EAC? You can post the screenshot here, and don't forget to cover your personal information.
Does OWA work as normal?

As SethWH mentioned, the error you provided may be caused by the server does not have available disk space. Here is the same error for your reference: IIS 7.5 Unable to write configuration file.
Please Note: Since the web site is not hosted by Microsoft, the link may change without notice. Microsoft does not guarantee the accuracy of this information.

If EAC still cannot work after freeing up disk space, here are more suggestions for you:
1. Please check and make sure all needed Exchange services are running well.
2. Recycle MSExchangeECPAppPool in Application Pools from IIS Manager. Application Pools > MSExchangeECPAppPool > Recycle.
3. Run UpdateCas.ps1 and UpdateConfigFiles.ps1 from the exchange bin directory C:\Program Files\Microsoft\Exchange Server\V15\Bin.
After that, use the following command to restart IIS:

 iisreset /noforce

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