Hello @MichaelHan-MSFT ,
You can use the following suggestions:
1.Reset the cache(index file)
Site settings >> Site collection object cache >> check the box for “Force this server to reset its disk based cache”
It will be regenerate cache(index file) when you accessing this page next time.
2.Install the latest version of security update for SharePoint Server 2019.
If clean the cache does not work, it is recommended that you install the latest version of security update for SharePoint Server 2019.
Microsoft Official Resource:
Description of the security update for SharePoint Server 2019: October 13, 2020
Here is a similar case for reference: Error occured with Blob Cache in
Thanks,
Echo Du
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