can we combine app and wfe together in to custom role in SHarePoint minrole?
Yes you can, but in general you shouldn't. How well this performs will depend on various factors, such as concurrent user count, usage of backend services (i.e. SharePoint 2010 Workflows), etc.
Hi @sns1 ,
I agree with @trevorseward.
You could use custome role to combine Appplication and Web Front-End.
More information, please refer to this article.
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