Unable to open documents on UserProfileDisks after Office365 upgrade to 2107 or 2108

Kristján Guðnason 1 Reputation point
2021-09-25T11:20:40.527+00:00

When testing upgrade of Office365 on my RD host I got a problem opening office documents from desktop or documents that reside on a user profile disk.

Word will show the "starting" splash screen for 10-15 minutes and eventually do nothing then close. Same with Excel

If I copy the same documents to the users Home drive thats on the network, the document opens normally, as in super quick.

I tested this with Office 365 Enterprise on:

Current Channel (2108) = Problem
Monthly Enterprise (2107) = Problem
Semi-Annual Enterprise (2102) = No problem

Server OS is 2012 R2

Remote Desktop
Remote Desktop
A Microsoft app that connects remotely to computers and to virtual apps and desktops.
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Office Management
Office Management
Office: A suite of Microsoft productivity software that supports common business tasks, including word processing, email, presentations, and data management and analysis.Management: The act or process of organizing, handling, directing or controlling something.
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  1. Viki Ji_MSFT 4,421 Reputation points
    2021-09-27T02:08:13.937+00:00

    Hi anonymous user,
    Welcome to Q&A forum!

    This may be because Windows Server 2012 R2 no longer supports Microsoft 365 Apps.

    The official documentation states:
    "As of January 14, 2020, Microsoft 365 Apps isn’t supported on Windows Server 2012 R2, even though Windows Server 2012 R2 is supported until October 10, 2023.
    You can continue to use the most current versions of Microsoft 365 Apps on Windows Server 2012 R2, but Microsoft 365 Apps won’t be supported."

    For more information about Microsoft 365 Apps system requirements, please refer to: System requirements for Microsoft 365 and Office.

    Thanks for your understanding!

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