Despite the fact that our users are (not for long) admins on their PCs with Windows 10 20H2 and have the September 2021 update, when we applied the September 2021 update to the print server everyone lost connectivity to all the printers. The only way to get the printers back was to set:
RpcAuthnLevelPrivacyEnabled to 0
on both the workstations and the server. The server is 2012 R2. Did I miss something? Driver updates and firmware updates on the printers didn't help. We would prefer to have these security features in place but printing is essential to our business.