We have an issue with a DC that is Server 2016. We installed the January 2022 patch and replication started to fail. We know there was an OOB patch, but we didn't apply it. We removed the January 2022 patch and everything worked again. We decided to skip February and installed the SSU and patch for March 2022 and the same issue happened. RPC 1722 server is unavailable error.
We have other Server 2016 DC's that got the same patches and no issues. Has anyone seen this problem?