question

@vkdotnet

You can use the static ServerManager.OpenRemote() method to geta remote system, then get the application based on this ServerManager instance. you can use the following code as a reference:

ServerManager.OpenRemote(String) Method.

 protected void test()
    {
        protected Application application;
        using (var iis = ServerManager.OpenRemote("IIS"))  //or by IP "1.1.1.1"
        {
            var site = iis.Sites[WebSiteName];
            var appPath = "/" + VirtualDirectoryPath;
            application = site.Applications[appPath];                      
        }
    }

If the answer is the right solution, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.