In many of the screencast in this series I have moved a VM around my demo setup, however there has only been the one copy of it whether it was on a scale-out file server, in a cluster or both. In any production environment you would want to augment this with additional disaster recovery techniques including have a backup of the key virtual machines somewhere.
Replica in Windows Server 2012 is a partial answer to this. You setup a process to make an offline copy of a given virtual machine (VM) on another server and continually keep it updated. This replica VM can be updated over “UK speed” (don’t get me started!) broadband and you can also maintain up to 4 roiling snapshots enabling you to go back past a data error you may want to correct. This screencast shows you how to set it up ..