Apple vs Microsoft - sub-pixel differences
When Apple's Safari browser was released several articles on the difference between how pages looked were posted.
The majority of Windows users appear to prefer the way Microsoft renders font's and Apple users appear to prefer the way Apple does it. It turns out Microsoft tries to optimize for the screen and Apple tries to match the print output What is your preference?
Apple and Microsoft have always disagreed in how to display fonts on computer displays.
From the article: Coding Horror: What's Wrong With Apple's Font Rendering?
I had read a few complaints that OS X font rendering was a little wonky
From the article: First look: Safari 3 beta on Windows vs. Firefox 2 and IE7
I think that the Safari 3 fonts are fuzzy and difficult to read.