You can deploy App-V 5.1 packages using an Electronic Software Distribution (ESD) solution. For information about planning to deploy App-V packages with an ESD, see Planning to Deploy App-V 5.1 with an Electronic Software Distribution System.
To deploy App-V packages with Microsoft System Center 2012 Configuration Manager, see Introduction to Application Management in Configuration Manager
How to deploy virtualized packages using an ESD
Describes the methods you can use to deploy App-V packages by using an ESD
How to Enable Only Administrators to Publish Packages by Using an ESD
Explains how to configure the App-V client to enable only administrators to publish and unpublish packages when you’re using an ESD.