Starting in App-V 5.0 SP3, you can configure the App-V client so that only administrators (not end users) can publish or unpublish packages. In earlier versions of App-V, you could not prevent end users from performing these tasks.
To enable only administrators to publish or unpublish packages
Navigate to the following Group Policy Object node:
Computer Configuration > Policies > Administrative Templates > System > App-V > Publishing.
Enable the Require publish as administrator Group Policy setting.
To alternatively use PowerShell to set this item, see How to Manage App-V 5.0 Packages Running on a Stand-Alone Computer by Using PowerShell.