Visual Studio supports profiling a Python application when using CPython-based interpreters.
Profiling is started through the Analyze > Launch Python Profiling menu command, which opens a configuration dialog:
When you select OK, the profiler runs and opens a performance report through which you can explore how time is spent in the application:
For an overview, see the following
For a walkthrough demonstration, see the Profiling with Python Tools for Visual Studio video (8m52s).
Profiling for IronPython
Because IronPython is not a CPython-based interpreter, the profiling feature above will not work.
Instead, use the Visual Studio .NET profiler by launching
ipy.exe directly as the target application, using the appropriate arguments to launch your startup script. Include
-X:Debug on the command line to force all of your Python code to be debuggable and profilable. This results in a performance report including time spent both in the IronPython runtime and you code. Your code is identified using mangled names.
Alternately, IronPython has some of its own built-in profiling but there's currently no good visualizer for it. See An IronPython Profiler (MSDN blogs) for what's available.