GloWGR:整個基因組迴歸GloWGR: Whole genome regression

注意

不再支援使用發光管道轉換器執行 SAIGE 和 SAIGE-GENE。Running SAIGE and SAIGE-GENE with the Glow Pipe Transformer is no longer supported. 建議您改用 GloWGR 來執行關聯測試。We recommend using GloWGR to perform association tests instead. 如需發光輸送轉換器的另一個範例,請參閱 使用管道轉換器的變異注釋For another example of the Glow Pipe Transformer, see Variant Annotation using Pipe Transformer.

GloWGR是一種可調整的整個基因組回歸方法,與使用專案發光的開放原始碼中的Regeneron 遺傳學導論 Center共同作業開發。GloWGR is a scalable whole genome regression method developed in collaboration with the Regeneron Genetics Center in open source with Project Glow. GloWGR 是單一節點工具的分散式版本 regenie (查看 bioRxiv preprint) 的 第二個版本GloWGR is a distributed version of the single-node tool regenie (see the second version of the bioRxiv preprint). GloWGR 是符合企業需求的工具,可針對整個基因組回歸的其他方法提供相等的精確度,但速度會有較大規模的改進。GloWGR is an enterprise-ready tool that provides equivalent accuracy to other methods for whole genome regression, but with an order-of-magnitude improvement in speed.

建立 GloWGR 叢集Create a GloWGR cluster

在 Databricks Runtime 7.0 中執行 Genomics 和更新版本的 GloWGR。Run GloWGR in Databricks Runtime 7.0 for Genomics and above.

範例筆記本Example notebook

GloWGR 筆記本GloWGR notebook

取得筆記本Get notebook