Block syncing of specific file types
You can prevent users from uploading specific file types when they sync their OneDrive files.
This setting prevents file types from being uploaded but not downloaded. If users already have blocked file types in their OneDrive, the files will sync to their computer, but any changes they make on their computer won't be uploaded.
To block uploading of specific file types
If you have Office 365 Germany, sign in to the Microsoft 365 admin center, then browse to the SharePoint admin center and open the Sharing page.
If you have Office 365 operated by 21Vianet (China), sign in to the Microsoft 365 admin center, then browse to the SharePoint admin center and open the Sharing page.
Select the Block upload of specific file types check box.
Enter the file name extensions you want to block, for example: exe or mp3.
Do not include the periods with the extensions, or any other punctuation, spaces, or special characters.
When you configure this setting, it takes approximately 8 hours for the OneDrive sync app to detect it and apply the change.
For info about setting this sync app restriction by using PowerShell, see Set-SPOTenantSyncClientRestriction. For info about using a policy to block upload of specific files, see Exclude specific kinds of files from being uploaded.